Rachel Anderson

0000-0003-2191-0655

Science Team Leader (Biological sciences; Microbiology; Biomedical and clinical sciences; Neurosciences; Nutrition and dietetics; Psychology; Biological psychology)

Palmerston North, New Zealand

I am the Science Team Leader for the Gut Model Systems Team in the Smart Foods and Bioproducts Group at AgResearch. Our team is based in Te Ohu Rangahau Kai on the Massey University campus in Palmerston North, New Zealand. My research focuses on how foods and food ingredients affect the interactions between the host and its resident bacteria, and how these alter intestinal barrier function. I am also interested in how intestinal barrier dysfunction leads to chronic inflammation and illnesses in other parts of the body, such as the brain via the gut-brain axis. I am the Programme Leader for the MBIE Endeavour "Dairy Products for Smarter Lives" programme which is a 5-year research programme aiming to understand how foods can be used to modify the gut-brain axis and in turn affect behaviour and cognition. Within this programme my research focuses on how intestinal barrier dysfunction can lead to systemic inflammation that results in neuroinflammation.

Publications

Comparative innate immune interactions of human and bovine secretory IgA with pathogenic and non-pathogenic bacteria
Promotility action of the probiotic Bifidobacterium lactis HN019 extract compared with prucalopride in isolated rat large intestine
Short communication: Early-lactation, but not mid-lactation, bovine lactoferrin preparation increases epithelial barrier integrity of Caco-2 cell layers
Live Faecalibacterium prausnitzii does not enhance epithelial barrier integrity in an apical anaerobic co-culture model of the large intestine
Influence of bovine whey protein concentrate and hydrolysate preparation methods on motility in the isolated rat distal colon
Understanding how commensal obligate anaerobic bacteria regulate immune functions in the large intestine
Gene Expression Changes in the Colon Epithelium Are Similar to Those of Intact Colon during Late Inflammation in Interleukin-10 Gene Deficient Mice
Pilot-scale extraction and antimicrobial activity of crude extract from ovine neutrophils
Isolation and characterisation of proline/arginine-rich cathelicidin peptides from ovine neutrophils
Factors affecting the antimicrobial activity of ovine-derived cathelicidins against E. coli 0157:H7
The probiotic Escherichia coli Nissle 1917 inhibits propagating colonic contractions in the rat isolated large intestine
Lactobacillus fermentum AGR1487 cell surface structures and supernatant increase paracellular permeability through different pathways
Antimicrobial fragments of the pro-region of cathelicidins and other immune peptides
Moderate levels of dietary sheep milk powder reduce experimentally induced colonic inflammation in rats
Human oral isolate Lactobacillus fermentum AGR1487 reduces intestinal barrier integrity by increasing the turnover of microtubules in Caco-2 cells
Antimicrobial peptides isolated from the blood of farm animals
Lactobacillus plantarum MB452 enhances the function of the intestinal barrier by increasing the expression levels of genes involved in tight junction formation
Antimicrobial Activity and Bacterial-Membrane Interaction of Ovine-Derived Cathelicidins
Live Faecalibacterium prausnitzii in an apical anaerobic model of the intestinal epithelial barrier
Are Postbiotics the Long Sought-After Solution for a Leaky Gut?
Post-weaning effects of milk and milk components on the intestinal mucosa in inflammation
Erratum: Isolation and characterisation of proline/arginine-rich cathelicidin peptides from ovine neutrophils (Biochemical and Biophysical Research Commmunications (2003) 312 (1139-1146))
Effect of kibble and raw meat diets on peripheral blood mononuclear cell gene expression profile in dogs
Human oral isolate Lactobacillus fermentum AGR1487 induces a pro-inflammatory response in germ-free rat colons
Ruminant Milk-Derived Extracellular Vesicles: A Nutritional and Therapeutic Opportunity?
A bioactive bovine whey protein extract improves intestinal barrier function in vitro
Smart Foods from the pastoral sector - Implications for meat and milk producers
Isolation and characterisation of antimicrobial peptides from deer neutrophils
The role of cell surface architecture of lactobacilli in host-microbe interactions in the gastrointestinal tract
Cryopreservation of monocytes or differentiated immature DCs leads to an altered cytokine response to TLR agonists and microbial stimulation
Regulation of tight junction permeability by intestinal bacteria and dietary components
Lactobacillus plantarum DSM 2648 is a potential probiotic that enhances intestinal barrier function
Investigation of morphological changes to Staphylococcus aureus induced by ovine-derived antimicrobial peptides using TEM and AFM
Ovine antimicrobial peptides: New products from an age-old industry
Influence of the Fruit Juice Carriers on the Ability of Lactobacillus plantarum DSM20205 to Improve in Vitro Intestinal Barrier Integrity and Its Probiotic Properties
Live Faecalibacterium prausnitzii induces greater TLR2 and TLR2/6 activation than the dead bacterium in an apical anaerobic co-culture system
Bovine dairy complex lipids improve in vitro measures of small intestinal epithelial barrier integrity
Short communication: Processed bovine colostrum milk protein concentrate increases epithelial barrier integrity of Caco-2 cell layers
Whole tissue homogenization preferable to mucosal scraping in determining the temporal profile of segmented filamentous bacteria in the ileum of weanling rats
Lactiplantibacillus plantarum ST-III and Lacticaseibacillus rhamnosus KF7 Enhance the Intestinal Epithelial Barrier in a Dual-Environment In Vitro Co-Culture Model

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Julie Dalziel

Science Team Leader - Physiology & Health - Palmerston North, New Zealand

Julie Dalziel

Dulantha Ulluwishewa

Research Scientist

Dulantha Ulluwishewa

Rachel Anderson

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