Vince Carbone

Publications

• Plasma Protein Binding Structure-Activity Relationships Related to the N-Terminus of Daptomycin
• Applied and environmental microbiology
• Structural characterisation of methanogen pseudomurein cell wall peptide ligases homologous to bacterial MurE/F murein peptide ligases
• Structural determination of archaeal UDP‐N‐acetylglucosamine 4‐epimerase from Methanobrevibacter ruminantium M1 in complex with the bacterial cell wall intermediate UDP‐N‐acetylmuramic acid
• Good host - bad host: molecular and evolutionary basis for survival, its failure, and virulence factors of the zoonotic nematode Anisakis pegreffii
• Mapping immunogenic epitopes of an adhesin-like protein from Methanobrevibacter ruminantium M1 and comparison of empirical data with in silico prediction methods
• The potentially beneficial central nervous system activity profile of ivacaftor and its metabolites
• Molecular and evolutionary basis for survival, its failure, and virulence factors of the zoonotic nematode Anisakis pegreffii
• Archaeal pseudomurein and bacterial murein cell wall biosynthesis share a common evolutionary ancestry
• Crystal Structures of Bacterial Pectin Methylesterases Pme8A and PmeC2 from Rumen Butyrivibrio
• Structure of monkey dimeric dihydrodiol dehydrogenase in complex with isoascorbic acid
• Structure of aldehyde reductase in ternary complex with a 5-arylidene-2,4-thiazolidinedione aldose reductase inhibitor
• Carboxymethylated pyridoindole antioxidants as aldose reductase inhibitors: Synthesis, activity, partitioning, and molecular modeling
• Aspartyl protease inhibitor pepstatin binds to the presenilins of Alzheimer's disease
• The RNA-dependent-RNA polymerase, an emerging antiviral drug target for the hendra virus
• Unusual binding mode of the 2S4R stereoisomer of the potent aldose reductase cyclic imide inhibitor fidarestat (2S4S) in the 15 K crystal structure of the ternary complex refined at 0.78 Å resolution: Implications for the inhibition mechanism
• Structure and evolution of the archaeal lipid synthesis enzyme sn-Glycerol-1-phosphate dehydrogenase
• Interaction of phthalates and phenoxy acid herbicide environmental pollutants with intestinal intracellular lipid binding proteins
• Molecular characterisation of the haemagglutinin glycan-binding specificity of egg-adapted vaccine strains of the pandemic 2009 H1N1 swine influenza a virus
• Molecular characterization of the receptor binding structure-activity relationships of influenza B virus hemagglutinin
• Structures of dimeric dihydrodiol dehydrogenase apoenzyme and inhibitor complex: Probing the subunit interface with site-directed mutagenesis
• Structural and functional features of dimeric dihydrodiol dehydrogenase
• Structure of 3(17)α-hydroxysteroid dehydrogenase (AKR1C21) holoenzyme from an orthorhombic crystal form: An insight into the bifunctionality of the enzyme
• Characterization of two isoforms of mouse 3(17)α-hydroxysteroid dehydrogenases of the aldo-keto reductase family
• The crystal structure of methenyltetrahydromethanopterin cyclohydrolase from Methanobrevibacter ruminantium
• Structure-based discovery of human L-xylulose reductase inhibitors from database screening and molecular docking
• Drug-drug plasma protein binding interactions of ivacaftor
• Correlation of binding constants and molecular modelling of inhibitors in the active sites of aldose reductase and aldehyde reductase
• Structure-based design of inhibitors of human L-xylulose reductase modelled into the active site of the enzyme
• Enzymatic characteristics of an aldo-keto reductase family protein (AKR1C15) and its localization in rat tissues
• Structure of aldehyde reductase holoenzyme in complex with the potent aldose reductase inhibitor fidarestat: Implications for inhibitor binding and selectivity
• A 1A o-ATP synthase of Methanobrevibacter ruminantium couples sodium ions for ATP synthesis under physiological conditions
• Structure of aldehyde reductase in ternary complex with coenzyme and the potent 20α-hydroxysteroid dehydrogenase inhibitor 3,5-dichlorosalicylic acid: Implications for inhibitor binding and selectivity
• A salicylic acid-based analogue discovered from virtual screening as a potent inhibitor of human 20α-hydroxysteroid dehydrogenase
• Structure of the tetrameric form of human L-xylulose reductase: Probing the inhibitor-binding site with molecular modeling and site-directed mutagenesis
• Crystal Structure of Human L-Xylulose Reductase Holoenzyme: Probing the Role of Asn107 with Site-Directed Mutagenesis
• Isolation and Molecular Characterization of a Novel Podo-virus BIS08P22 having a Unique Terminase Enzyme Representing a new Genus in Class Caudoviricetes
• Sialylation of Asparagine 612 Inhibits Aconitase Activity during Mouse Sperm Capacitation; a Possible Mechanism for the Switch from Oxidative Phosphorylation to Glycolysis
• High-level nitrofurantoin resistance in a clinical isolate of Klebsiella pneumoniae: a comparative genomics and metabolomics analysis
• The crystal structure of methanogen McrD, a methyl‐coenzyme M reductase‐associated protein
• Feed additives for methane mitigation: Recommendations for identification and selection of bioactive compounds to develop antimethanogenic feed additives
• Structural characterisation of nucleotide sugar short‐chain dehydrogenases/reductases from the thermophilic pseudomurein‐containing methanogen Methanothermobacter thermautotrophicusΔH
• Crystal Structure of the Multidomain Pectin Methylesterase PmeC5 from Butyrivibrio fibrisolvens D1T