FBP 56120 (pub 3133) Trace Metals in Hairs - Submission.pdf (766.27 kB)

Trace Metal Ions in Hair from Frequent Hair Dyers in China and the Associated Effects on Photo-oxidative Damage

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journal contribution
posted on 2023-05-03, 20:36 authored by Jolon Dyer, Santanu Deb-Choudhury, Ying Tang, Qiao Li
Human hairs are subject to oxidative modification when exposed to sunlight. In the present study, samples of human hair from Chinese volunteers that included frequent hair dyers and non-dyers were analyzed for metal ions such as iron, copper, magnesium, aluminum, zinc and lead. The generation of hydroxyl radicals during UVA (315–400 nm) photoageing was quantified and oxidative damages characterized by proteomic and SEM analysis. It was concluded that high levels of metal ions, particularly those derived from iron and copper, identified in the dyed hairs are associated with enhanced photoformation of hydroxyl radicals and resultant photooxidative damage of the hair. Reactive oxygen species, including hydroxyl radicals, generated via an electron transfer mechanism with hair photosensitizers react with hair proteins. Proteomic analysis of hair samples from frequent hair dyers, regardless of age and gender, showed an almost 1.6 fold increase in the protein oxidative modification levels compared to the undyed samples. As a result, a more pronounced physical damage including fragmentation and cross-linkage of cuticle scales was observed on the surface of dyed hair samples during the photoageing. This work is aimed at better understanding the role of metal ions in dyed hairs and their possible role in photosensitizing hair proteins. The results from this study are anticipated to contribute to the improved development of hair coloring cosmetics and hair care products.


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© 2016 Elsevier B.V. All rights reserved.


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Journal title

Journal of Photochemistry & Photobiology, B: Biology




Tang, Y., Dyer, J. M., Deb-Choudhury, S., & Li, Q. (2016). Trace metal ions in hair from frequent hair dyers in China and the associated effects on photo-oxidative damage. Journal of Photochemistry & Photobiology, B: Biology, 156, 35-40.

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