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The genome sequence of the anthelmintic-susceptible New Zealand Haemonchus contortus

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posted on 2023-05-03, 18:24 authored by Nik PalevichNik Palevich, Paul MacleanPaul Maclean, Abdul Baten, Richard ScottRichard Scott, Dave LeathwickDave Leathwick
The barber’s pole worm, Haemonchus contortus, is one of the most economically important and common pathogenic nematodes infecting small ruminants worldwide (Laing, et al. 2013; Schwarz, et al. 2013). Although this parasite can be controlled using anthelmintic drugs, its remarkable natural tendency to develop resistance threatens the global livestock industry. We provide a high-quality draft genome of the anthelmintic-susceptible H. contortus NZ_Hco_NP field strain isolated from pasture-grazed New Zealand sheep. H. contortus was selected for genome sequencing in order to identify the genetic mechanisms that evoke parasite exsheathment and anthelmintic drug resistance.

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Rights statement

The Author(s) 2019. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in anymedium, provided the original work is properly cited.

Language

  • English

Does this contain Māori information or data?

  • No

Publisher

Oxford University Press

Journal title

Genome Biology and Evolution

ISSN

1759-6653

Citation

Palevich, N., Maclean, P. H., Baten, A., Scott, R. W., & Leathwick, D. L. (2019). The genome sequence of the anthelmintic-susceptible New Zealand Haemonchus contortus. Genome Biology and Evolution, 11(7), 1965–1970. doi:10.1093/gbe/evz141

Funder

MSD Animal Health

Job code

33461

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