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A large and diverse collection of bovine genome sequences from the Canadian Cattle Genome Project

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posted on 2023-05-03, 15:24 authored by Paul Stothard, Xiaoping Liao, Adriano S. Arantes, Mary D. Pauw, Colin Coros, Graham S. Plastow, Mehdi Sargolzaei, John J. Crowley, John A. Basarab, Flavio Schenkel, Stephen Moore, Stephen Miller
Background: The Canadian Cattle Genome Project is a large-scale international project that aims to develop genomics-based tools to enhance the efficiency and sustainability of beef and dairy production. Obtaining DNA sequence information is an important part of achieving this goal as it facilitates efforts to associate specific DNA differences with phenotypic variation. These associations can be used to guide breeding decisions and provide valuable insight into the molecular basis of traits. Findings: We describe a dataset of 379 whole-genome sequences, taken primarily from key historic Bos taurus animals, along with the analyses that were performed to assess data quality. The sequenced animals represent ten populations relevant to beef or dairy production. Animal information (name, breed, population), sequence data metrics (mapping rate, depth, concordance), and sequence repository identifiers (NCBI BioProject and BioSample IDs) are provided to enable others to access and exploit this sequence information. Conclusions: The large number of whole-genome sequences generated as a result of this project will contribute to ongoing work aiming to catalogue the variation that exists in cattle as well as efforts to improve traits through genotype-guided selection. Studies of gene function, population structure, and sequence evolution are also likely to benefit from the availability of this resource.


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© 2015 Stothard et al. Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (, which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver ( applies to the data made available in this article, unless otherwise stated.


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BioMed Central

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Stothard, P., Liao, X., Arantes, A. S., De Pauw, M., Coros, C., Plastow, G. S., Sargolzaei, M., Crowley, J. J., Basarab, J. A., Schenkel, F., Moore, S., & Miller, S. P. (2015). A large and diverse collection of bovine genome sequences from the Canadian Cattle Genome Project. GigaScience, 4, 49. doi:10.1186/s13742-015-0090-5

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