Validating foods for healthy cognitive ageing: A gut-brain axis cell model approach

<p dir="ltr">As the global population ages, the prevalence of neurodegenerative disorders is on the rise. Diet plays a crucial role in brain health, and understanding gut-brain axis interactions is key to identifying food-based interventions. Traditional methods, such as human studies and animal models, face limitations due to the long-term nature of cognitive decline and ethical concerns.</p><p dir="ltr">This presentation introduces a novel cell culture model that simulates the gut-brain axis. This model offers a more efficient and ethical approach to screening food ingredients for their potential benefits on brain health. By dissecting the mechanisms of action, we can develop evidence-based claims for food-related brain health interventions. This model holds promise for accelerating the development of dietary strategies to support healthy ageing.</p><p dir="ltr"><b>Key takeaways:</b></p><ul><li>The gut and the brain are connected via signalling pathways known as the gut-brain axis.</li><li>Diet is an important risk factor for neurodegeneration later in life.</li><li>How a cell model of the gut-brain axis can help develop new food products for brain health benefits.</li></ul><p></p>